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Introduction: An Invitation to Change Your Life

Part I The Genetic Revolution: Let’s Live Healthier — and Longer
  • Know Your Genetic Makeup and Take Charge of Your Future

  • Use Nature to Determine Your Nurture

  • The Genetic Answer to Generic Risk Factors and Family History

  • What Genetic Testing Can Detect

  • Category 1: Risk for Future Disease

  • Category 2: Disease That Affects You Right Now

  • Category 3: Diseases You Carry That Do Not Affect You

  • Is Genetic Testing Right For You

  • Medicine’s New Pincer Movement – Going on the
    Offensive against Disease
  • Discovering the Structure of DNA

  • The Double Helix Structure of DNA

  • Genetic Variants — the Good, the Bad, and the Neutral

  • 0.5 Percent Makes All the Difference

  • The Human Genome Project

  • What All of this Means for You and Your Health

  • Chapter 3 Genetic Screening—How It Works for You
  • Genetic Testing

  • Single-Gene Sequencing

  • Arrays

  • Full-Genome Sequencing

  • Genetic Analysis

  • Genetic Screening Panels

  • The Disease Matrix and Reflex Analysis

  • The Genetic Report

  • Chapter 4 Become Informed about Genetic Screening: Who, What, & Where
  • Behind the Scenes of Genetic Research and Development

  • Research Genomics vs. Personal Genomics

  • Moving From Research to Personal Genomics

  • The Laboratory

  • Genetic Analysis

  • Results Delivery

  • An Overview of the Entire Process

  • Direct-to-Consumer Genetic Screening

  • Other Providers of Genetic Screening

  • Fear, Anxiety, and Genetic Screening

  • Calculation of Genetic Risk

  • Are Preliminary Studies Useful?

  • How Valid Are the Results?

  • What You Should Know About Regulation

  • Genetic Information and Confidentiality

  • HMOs, Health Insurance Coverage, and Genetically
    Tailored Insurance

  • Read the Fine Print

  • The Five Most Important Questions to Ask –
    And the Acceptable Answers
Part II Outsmart Your Genetic Destiny with Predictive Medicine
  • The Far-Reaching Consequences of Obesity

  • New Weapons in the Battle of the Bulge

  • The Weight of Your DNA

  • Sizing Up a Fat Gene

  • Other Fat Genes

  • Personalized Prevention and Treatment

  • Genetically Tailored Fitness

  • Will Weight-Loss Medications Work For You?

  • Will Weight-Loss Surgery Work For You?

  • Tipping the Scale in Our Favor with Genetic Screening

  • Nutrition, Fitness, and Weight-Loss Panels

  • Chapter 6 Prospective Parents—Becoming Pregnant &
    Protecting Your Future Children
  • Protecting Our Most Precious Resource

  • Family Planning in the 21st Century

  • Preimplantation Genetic Screening

  • Invasive Prenatal Diagnosis

  • Noninvasive Prenatal Screening

  • Genetic Screening with Assisted Reproductive Technologies

  • Adoption

  • Au Naturel

  • Genetic Screening of Prospective Parents

  • Fertility Issues

  • Orphan Diseases

  • Common Diseases

  • Preconception Genetic Screening: The Pythia Approach

  • Chapter 7 Newborns and Children—Protecting Those Most Dear to Us
  • Personal Identification and Safety

  • Genetic Screening of Newborns and Children

  • Screening for the Causes of Sudden Infant Death Syndrome (SIDS)

  • Screening for Autism

  • Protecting Your Child from Multiple Sclerosis

  • Dyslexia – the Genetic Component

  • Identifying Attention-Deficit/Hyperactivity Disorder (ADHD)

  • Screening to Prevent Obesity and Diabetes

  • Predicting and Preventing Alzheimer’s Disease

  • Genetic Causes of Asthma

  • Battling Cancer from Day One

  • Breast Cancer

  • Skin Cancer

  • Lung Cancer

  • Chapter 8 Protecting Your Cardiovascular Health by Beating Your DNA
  • Protecting the Beat of Life

  • The Genetics of Longevity

  • Outsmarting a Frailty Gene

  • Using Predictive Medicine to Avoid Sudden Death

  • Protecting your Arteries with Predictive Medicine

  • Reducing Stroke Risk and Avoiding Disability

  • Avoiding Brain Aneurysms

  • Averting Heart Failure

  • Sounding the Alarm on the Silent Killer: High Blood Pressure

  • Genetically Tailored Prevention

  • Genetically Tailored Lifestyles for Cardiovascular Health

  • Genetically Tailored Medications

  • Chapter 9 A New Strategy in Our War against Alzheimer’s Disease
  • Protecting the Spark of Life

  • Understanding Alzheimer’s

  • The Alzheimer’s War

  • Know Thine Enemy

  • The APOE Genetic Variants

  • Alzheimer’s Risk: Other Genetic Variants

  • Genetically Tailored Prevention

  • Build and Maintain a Cognitive Reserve

  • What’s Good for the Heart is Good for the Head

  • Prevention in a Pill

  • Complementary Prevention

  • Monitoring Your Cognition

  • Treatment
  • Chapter 10 Predict, Prevent, and Prevail over Cancer
  • Predict, Prevent, Prevail

  • Protecting Ourselves and Our Family against Cancer

  • Skin Cancer

  • Genetically Tailored Prevention

  • Colorectal Cancer

  • Genetically Tailored Prevention

  • Prostate Cancer

  • Genetically Tailored Prevention

  • Protecting the Breath of Life against Addiction and Lung Cancer

  • Genetically Tailored Prevention

  • Strategy 1: For Current Smokers

  • Strategy 2: For Current Nonsmokers with a Predisposition to Nicotine Addiction

  • Strategy 3: For Nonsmokers Exposed to Secondhand Smoke

  • Genetically Tailored Treatment

  • Going on the Offensive in our Battle against Breast and
    Ovarian Cancers

  • Understanding the Genetics of Breast and Ovarian Cancer

  • Using Comprehensive Screening to Gain an Invaluable Advantage

  • Genetically Tailored Prevention

  • Lifestyle

  • Pregnancy and Breastfeeding

  • Breast Examinations

  • Mammograms, MRIs, and Ultrasounds

  • Genetically Tailored Chemoprevention and Chemotherapy

  • Surgical Prevention

  • Men and Breast Cancer

  • Prevent and Prevail

Afterword Our Genetic Manifest Destiny
  • Our Genetic Manifest Destiny

  • Next-Generation Pharmaceutical Clinical Trials and Genetically
    Tailored Medications

  • Gene Therapy and Genetic Engineering

  • Animal Genetic Testing

  • There’s a Gene for That

  • The Genetic Revolution



References

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